Bioactive Small Molecules
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Filtered Search Results
Crescent Chemical Co Inc BRIJ 35 PRACT.
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Brij 35 pract. n ca. 23. HLB 16.9. Suitable for the isolation of functional membrane complexes (1). Also applied in chemiluminescence analysis (2, 3). Size - 100G Storage Conditions - +15 C TO +30 C Catalog Number - 15230.01
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Medchemexpress LLC MEDCHEMEXPRESS LLC
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5000370761 TMC647055 CHOLINE S 100MG
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Medchemexpress LLC MEDCHEMEXPRESS LLC
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5000370762 GW9508 10MM 1ML
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Medchemexpress LLC (2R)-5-(2-chlorophenyl)sulfanyl-4-hydroxy-2-(4-morpholin-4-ylphenyl)-2-thiophen-3-yl-1,3-dihydrop... | 2003234-63-5 | MFCD31560470 | 99.8% | 499.04 | C25H23ClN2O3S2 | 50 MG
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(R)-GNE-140 is the R-enantiomer of a potent lactate dehydrogenase A (LDHA) inhibitor used in biochemical and cellular research to probe LDH function and cancer metabolism. It exhibits nanomolar inhibition of LDHA and LDHB and has characterized purity, solubility, and storage properties suitable for in vitro and in vivo studies.
- Nanomolar inhibition of LDHA and LDHB (IC50 3 nM and 5 nM).
- R enantiomer is ~18-fold more potent than the S enantiomer.
- High chemical purity (99.77%) with enantiomeric excess ~99.14%.
- Solid, off-white to yellow appearance.
- Soluble in DMSO ≥ 50 mg/mL for in vitro use.
- Formulation suitable for in vivo dosing (≥ 2.5 mg/mL in 10% DMSO/40% PEG300/5% Tween-80/45% saline).
- Storage: powder at -20°C (stable for years) or 4°C for shorter term; in solvent store at -80°C or -20°C depending on duration.
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Apexbio Technology LLC GNE-9605 1536200-31-3 5mg
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GNE-9605 (CAS 1536200-31-3) is a selective brain-penetrant inhibitor of leucine-rich repeat kinase 2 (LRRK2) a kinase implicated in the pathogenesis of Parkinson s disease and Crohn s disease GNE-9605 exhibits high potency against LRRK2 with a reported Ki of 2 0 nM and IC50 of 18 7 19 nM In pharmacokinetic studies GNE-9605 demonstrates excellent metabolic stability in human hepatocytes and high oral bioavailability (90%) in rats In BAC transgenic mice expressing the G2019S LRRK2 mutation GNE-9605 potently inhibits LRRK2 Ser1292 autophosphorylation in a dose-dependent manner This compound supports preclinical investigations of LRRK2 signaling and its role in neurodegenerative disease
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Apexbio Technology LLC CGP 52432 139667-74-6 10mg
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CGP 52432 (CAS 139667-74-6) is a selective antagonist of the GABAB receptor exhibiting an IC50 of 85 nM By inhibiting GABAB receptor-mediated signaling pathways CGP 52432 modulates neurotransmitter release and alters neuronal activity This compound is widely utilized in neuroscience research to investigate GABAergic mechanisms underlying physiological and pathological processes and to support the development of therapeutic strategies targeting GABAB receptor function
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Medchemexpress LLC DT-3 acetate | 98.9% | 3294.07 | 10 MG
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DT-3 acetate is a membrane-permeable protein kinase G Iα (PKG Iα) inhibitory peptide that pharmacologically blocks cGMP-PKG signaling.
- Acts as a PKG Iα inhibitory peptide
- Pharmacologically blocks cGMP-PKG signaling
- Suitable for research in blood or cardio-cerebrovascular disease
- Useful in cardiovascular disease studies
- High purity of 98.9%
- Soluble in H2O at ≥ 100 mg/mL
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Cayman Chemical 1-Undecnoyl-rac-glycerol 500mg
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A monoacylglycerol that contains undecanoic acid at the sn-1 position; completely inhibits the growth of the bacteria B. cereus, B. subtilis, M. luteus, E. faecalis, and S. aureus at 250-1,500 mg/L; has antifungal activity against K. marxianus, S. cerevisiae, and C. maltosa at 0.1 and 0.3 mg/ml
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AXON MEDCHEM LLC GLP-1R AGONIST DMB 5MG
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NC3821772 GLP-1R AGONIST DMB 5MG
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Cayman Chemical ANTIBODY YH 239-EE 25mg
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A prodrug form of YH 239; inhibits the growth of OCI-AML-3 cells and halts the cell cycle at the sub-G1 phase and induces apoptosis in NB4 and MOLM-13 cells at 20 μM
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Cayman Chemical N N-dImethyl Heptylonhydro 5mg
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An analytical reference standard categorized as a cathinone; intended for research and forensic applications
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Selleck Chemical LLC LY3009120
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LY03009120 (DP-4978) is a potent pan-Raf inhibitor with IC50 of 44 nM 31-47 nM and 42 nM for A-raf B-Raf and C-Raf in A375 cells respectively LY03009120 induces autophagy Phase 1
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Medchemexpress LLC Angiogenin (108-122) (TFA) | 98.1% | 1895.00 | 25 MG
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Angiogenin (108-122) (TFA) | 98.1% | 1895.00 | 25 MG
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Medchemexpress LLC Glucagon (19-29), human | 64790-15-4 | 99.1% | 1352.53 | 50 MG
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Glucagon (19-29), human | 64790-15-4 | 99.1% | 1352.53 | 50 MG
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Medchemexpress LLC SAMS | 125911-68-4 | 96.84% | 1779.15 | 1 MG
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SAMS | 125911-68-4 | 96.84% | 1779.15 | 1 MG
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